Metabolic Syndrome. Focus on the Kidneys

Mikhailova L.V., Tynterova A.M., Rafalsky V.V., Kryukova N.O., Filimonkina Yu.A., Vakhnina K.V.

Immanuel Kant Baltic Federal University, Kaliningrad, Russia

This article examines the evolution of the concept of metabolic syndrome (MS) and its close association with the development of chronic kidney disease (CKD). MS is a cluster of disorders including abdominal obesity, insulin resistance, dyslipidemia, and arterial hypertension, which significantly increases the risk of developing cardiovascular complications, type 2 diabetes mellitus, and CKD. The incidence of MS and CKD continues to rise worldwide, resulting in high mortality, primarily from cardiovascular complications. The authors note the growing need for early detection and correction of metabolic risk factors, the need to develop methods for preclinical diagnosis of CKD in patients with MS, and a multidisciplinary approach to patient management. Key objectives include identifying early biomarkers of kidney damage and the widespread implementation of preventive strategies to reduce the risk of cardiovascular and renal complications in patients with MS.

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About the Authors

Larisa V. Mikhailova – Cand.Sci. (Med.), Associate Professor, Department of Therapy, Institute of Medicine and Life Sciences (MEDBIO), Immanuel Kant Baltic Federal University. Address: 14 Alexander Nevsky Str., Kaliningrad, 236041, Russia. Tel.: +7-962-265-14-66; E-mail: mihalysa@mail.ru. ORCID: 0000-0001-5070-5955
Anastasia М. Tynterova – Dr.Sci. (Med.), Senior Researcher. Baltic Center for Artificial Intelligence and Neurotechnology. Immanuel Kant Baltic Federal University. Address: 14 Alexander Nevsky Str., Kaliningrad, 236041, Russia. E-mail: antynterova@mail.ru. ORCID: 0000-0003-1743-4713
Vladimir V. Rafalskiy – Dr.Sci. (Med.), Professor, Head of the Department of General and Clinical Pharmacology, Institute of Medicine and Life Sciences (MEDBIO), Immanuel Kant Baltic Federal University. Address: 60 9th April St., Kaliningrad, 236016. Tel.: +7 (4012) 59-55-95, ext. 6709. E-mail: v.rafalskiy@mail.ru. ORCID: 0000-0002-2503-9580
Nadezhda O. Kryukova – Cand.Sci.(Med.), Associate Professor, Department of General and Clinical Pharmacology, Institute of Medicine and Life Sciences (MEDBIO), Immanuel Kant Baltic Federal University. Address: 60 9th April St., Kaliningrad, 236016. Tel.: +7 (4012) 59-55-95, ext. 6709. E-mail: krukovano@yandex.ru. ORCID: 0000-0002-2379-6764
Yulia A. Filimonkina – Teaching Assistant, Department of Therapy, Institute of Medicine and Life Sciences (MEDBIO), Immanuel Kant Baltic Federal University. Address: 60 9th April St., Kaliningrad, 236016. Tel.: +7 (4012) 59-55-95, ext. 6709. E-mail: j.filimonkina@mail.ru. ORCID: 0009-0000-1864-2448
Ksenia V. Vakhnina – 6-year Student student of the Higher School of Medicine, Institute of Medicine and Life Sciences (MEDBIO). Immanuel Kant Baltic Federal University. Address: 60 9th April St., Kaliningrad, 236016. Tel.: +7 (4012) 59-55-95, ext. 6709. E-mail: kseniya20024@gmail.com. ORCID: 0009-0006-6398-9890

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