Modern concepts of the role of asymptomatic hyperuricemia in the formation of chronic kidney disease and cardiovascular risk

Dudnikova A.V., Mekhrabov R.A., Alieva A.R., Gish Z.A., Leontyev A.A., Rasskazova D.A.

1) Clinic of the Kuban State Medical University, Krasnodar, Russia; 2) Kuban State Medical University, Krasnodar, Russia

Asymptomatic hyperuricemia is a term traditionally applied to conditions in which serum urate concentrations are elevated, but there are no symptoms or signs of diseases associated with precipitation of uric acid crystals, such as gout or uric acid kidney disease. According to a number of studies, hyperuricemia is associated with other disorders that are not directly related to crystal deposition (including chronic kidney disease – CKD, arterial hypertension, cardiovascular, and neurological diseases). The purpose of this review was to analyze modern literature on modern concepts of the etiology, pathogenesis, diagnostic criteria for asymptomatic hyperuricemia and its role in the formation of renal dysfunction, cardiovascular and metabolic disorders.

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About the Authors

Anna V. Dudnikova – Cand.Sci. (Med.), Cardiologist at the Clinic of the Kuban State Medical University. Address: 4/3 Zipovskaya st., Krasnodar, 350010; e-mail: avdudnikova@yandex.ru. ORCID: http://orcid.org/0000-0003-2601-7831, eLibrary SPIN: 7480-1992
Ruslan A. Mekhrabov – 6th-year Student at the Faculty of Medicine, Kuban State Medical University. Address: 4 Sedin st., Krasnodar, 350063; e-mail: rus.mekhrabrv@mail.ru
Anastasia R, Alieva – 6th-year Student at the Faculty of Medicine, Kuban State Medical University. Address: 4 Sedin st., Krasnodar, 350063; e-mail: ananastasiya00@mail.ru
Zamira A. Gish– 6th-year Student at the Faculty of Medicine, Kuban State Medical University. Address: 4 Sedin st., Krasnodar, 350063; e-mail: sofiaalieva0501@mail.ru
Andrey A. Leontyev – 6th-year Student at the Faculty of Medicine, Kuban State Medical University. Address: 4 Sedin st., Krasnodar, 350063; e-mail: aaleontyev00@icloud.com
Daria A. Rasskazova – 6th-year Student at the Faculty of Medicine, Kuban State Medical University. Address: 4 Sedin st., Krasnodar, 350063; e-mail: d_rasskazova@mail.ru

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