Analysis of the quality of life of patients with chronic kidney disease on dialysis therapy from the patient-centered healthcare perspective

Kotenko O.N., Dorofeeva E.G., Abolyan L.V.

1) Moscow City Scientific and Practical Center for Nephrology and Transplanted Kidney Pathology, Moscow City Research Center, Hospital No. 52, Moscow Healthcare Department, Moscow, Russia; 2) Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia; 3) Pirogov Russian National Research Medical University, Moscow, Russia

Background. The concept of health-related quality of life (QOL) as a key factor in patient-physician interaction is relevant for making management decisions to optimize medical care for nephrology patients from a patient-centered healthcare perspective.
Objective. Assessment and comparison of the QOL of patients with chronic kidney disease (CKD) on hemodialysis (HD) and peritoneal dialysis (PD) using a patient-centered approach to selecting and evaluating the effectiveness of medical care for this category of patients at the regional level of the Russian Federation.
Material and methods. Data were collected at the Moscow City Scientific and Practical Center for Nephrology and Transplanted Kidney Pathology of the Moscow Healthcare Department. The medical and social characteristics and health-related QOL of patients with CKD on HD and PD were examined. QOL was assessed using the KDQOL-SF™ v.1.3 questionnaire for dialysis patients. An analysis of the QOL dynamics of HD patients before and after their inclusion in the Telenephrocenter remote monitoring program was conducted, as well as a comparative analysis of the QOL of HD patients and PD patients included in the Telenephrocenter program. The study included 163 HD patients and 50 PD patients. The study was conducted from December 2023 to June 2024. Statistical analysis was performed using IBM SPSS.25 software.
Results. Patients with CKD on dialysis have low QOL. Differences in medical and social characteristics were identified between patients on HD and PD. Implementation of the Telenephrocenter program resulted in improved QOL among HD patients 3 and 6 months after program implementation. Patients on PD had better QOL indicators related to self-assessment of the physical component of health, while patients on HD had better indicators related to the psychological and social components of health.
Conclusion. Assessing the QOL of patients with CKD on dialysis is an important component of modern clinical trials conducted to optimize medical care for nephrology patients from a patient-centered perspective.

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About the Authors

Oleg N. Kotenko – Dr.Sci. (Med.), Deputy Chief Physician for Nephrology, Moscow Regional Research Center, Hospital No. 52, Moscow Healthcare Department, Address: 3/2 Pekhotnaya St., Moscow, 123182; Chief External Expert in Nephrology of the Moscow Healthcare Department and Northwestern Federal District, Pirogov Russian National Research Medical University. Address: Bldg. 7 1 Ostrovityanova St., Moscow; e-mail: olkotenko@yandex.ru. ORCID: 0000-0001-8264-7374,
Scopus ID: 57192109595. eLibrary SPIN: 8288-1016
Ekaterina G. Dorofeeva – Nephrologist, Consultative and Diagnostic Nephrology Department, Moscow Regional Research Center, Hospital No. 52, Moscow Healthcare Department. Address: 3/2 Pekhotnaya St., Moscow, 123182; ORCID: 0000-0002-8764-4495, Scopus ID: 58289278300
Liubov V. Abolyan – Dr.Sci. (Med.), Professor, N.A. Semashko Department of Public Health and Healthcare, Sechenov First Moscow State Medical University (Sechenov University). Address: Bldg 2, 8 Trubetskaya St., Moscow, 119048 8; e-mail: abolyan_l_v@staff.sechenov.ru. ORCID: 0000-0002-7644-8771, Scopus ID: 21733637200,
eLibrary SPIN: 5048-0170

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