ISSN 2075-3594 (Print)
ISSN 2414-9322 (Online)

ACE inhibitors and nephroprotection in chronic proteinuric nephropathies

S.V. Moiseev, MD, PhD, Prof; G.P. Arutyunov, MD, PhD, Prof; V.V. Fomin, MD, PhD

IM Sechenov Moscow Medical Academy, Russian State Medical University
ACE inhibitors slow irreversible worsening of renal function in chronic kidney disease with proteinuria, that is due not only to their blood pressure lowering effect, but also to their ability to reduce proteinuria. The reference prove of ACE inhibitors nephroprotective action was shown in trials REIN and AASK, in which ramipril was used.

Keywords

chronic kidney disease
proteinuria
ACE inhibitors
ramipril
nephroprotection

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