Heart rate variability, plasma renin activity and aldosterone level in chronic glomerulonephritis with arterial hypertension and normal renal function

N.Yu. Borovkova, MD, N.N. Borovkov, MD, PhD, Prof, B.N. Sidnev, MD, E.O. Obuhova MD

Nijnii Novgorod State Medical Academy

136 patients with chronic glomerulonephritis with normal renal function; 100 of them had normal renal function and 36 were normotensive. Heart rate variability was evaluated by of 24-h ECG monitoring. Plasma renin and aldosterone levels were measured in all patients. Heart rate variability disturbances became more prominent in patients with highest blood pressure. In patients with chronic glomeprulonephritis and arterial hypertension grade II and II plasma renin activity and aldosterone concentrations were increased. Conclusion. In chronic glomerulonephritis progression of arterial hypertension is associated with heart rate variability anomalies and plasma renin activity and aldosterone concentration increase.

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