Malignant neoplasms in the structure of mortality in kidney transplant recipients

Trushkin R.N., Isaev T.K., Sokolov A.A., Sokolov S.A., Vinogradov V.E., Isaeva A.M., Trushkina V.R.

1) State Budgetary Institution of Healthcare, Moscow Clinical Research Center, Hospital No. 52 of the Moscow Department of Healthcare, Moscow, Russia; 2) Department of Urology and Operative Nephrology with a Course in Oncourology, Patrice Lumumba Peoples' Friendship University of Russia, Moscow, Russia; 3) Federal State Budgetary Institution, Central Clinical Hospital with a Polyclinic of the Administrative Department of the President of the Russian Federation, Moscow, Russia; 4) Federal State Budgetary Educational Institution of Higher Education, Lomonosov Moscow State University, Moscow, Russia

Introduction. Kidney transplant recipients are at increased risk of malignant neoplasms compared to patients who have not undergone kidney transplantation, which is associated with the influence of specific factors inherent to this group.
Objective. To determine the role of malignant neoplasms in the structure of mortality in kidney transplant recipients.
Material and methods. The literature review was conducted using PubMed, Scopus, eLibrary, Web of Science, and Google Scholar databases. The search covered articles in Russian and English. From the initial selection of 69 publications, 28 of the most relevant studies from 2020 to 2025 were selected, corresponding to the objective of the review.
Conclusion. Kidney transplant recipients have increased incidence and mortality from malignant neoplasms compared to the general population. The high heterogeneity in cancer mortality rates among recipients across countries is likely due not only to regional differences in cancer incidence but also to the implementation of malignant neoplasm screening, which enables early detection of tumors.

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About the Authors

Trushkin Ruslan N. – Professor, DSc State Budgetary Institution of Healthcare, Moscow Clinical Research Center, Hospital No.52 of the Moscow Department of Healthcare. Address: 123182 Moscow, Pekhotnaya str., 3, Department of Urology and Operative Nephrology with a Course in Oncourology, Patrice Lumumba Peoples' Friendship University of Russia. Address: 117198 Moscow, Miklukho-Maklaya str., 6; e-mail: uro52@mail.ru. ORCID: 0000-0002-3108-0539
Isaev Teymur K. – Urologist, DSc State Budgetary Institution of Healthcare, Moscow Clinical Research Center, Hospital No.52 of the Moscow Department of Healthcare.
Address: 123182 Moscow, Pekhotnaya str., 3; e-mail: dr.isaev@mail.ru. ORCID: 0000-0003-3462-8616
Sokolov Aleksandr A. – PhD, Urologist Federal State Budgetary Institution, Central Clinical Hospital with a Polyclinic of the Administrative Department of the President of the Russian Federation. Address: 121359 Moscow, Marshal Timoshenko str., 15; tel.: +7 (985) 492-35-77; e-mail: salexdoc@gmail.com. ORCID: 0009-0007-0302-0428
Sokolov Sergey A. – Urologist State Budgetary Institution of Healthcare, Moscow Clinical Research Center, Hospital No.52 of the Moscow Department of Healthcare.
Address: 123182 Moscow, Pekhotnaya str., 3; e-mail: sergey.sokolow28@mail.ru. ORCID: 0009-0004-7016-2360
Vinogradov Vladimir E. – Head of the Consultative and Diagnostic Nephrology Department State Budgetary Institution of Healthcare, Moscow Clinical Research Center, Hospital No.52 of the Moscow Department of Healthcare. Address: 123182 Moscow, Pekhotnaya str., 3; e-mail: vino-gradoff@yandex.ru. ORCID: 0000-0002-0184-346X
Isaeva Anastasia M. – Gynecologist Federal State Budgetary Institution, Central Clinical Hospital with a Polyclinic of the Administrative Department of the President of the Russian Federation. Address: 121359 Moscow, Marshal Timoshenko str., 15; e-mail: antropik88@mail.ru. ORCID: 0009-0008-9362-4475
Trushkina Vasilisa R. – Student of the medical faculty 4Federal State Budgetary Educational Institution of Higher Education, Lomonosov Moscow State University.
Address: 119234 Moscow, Leninskie Gory Ter, 1; e-mail: vasilisa.trushkina.07@mail.ru

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