Principles of treatment of malignant neoplasms in kidney transplant recipients

Trushkin R.N., Sokolov A.A., Sokolov S.A., Isaev T.K., Isayeva A.M.

1) Moscow Clinical Research Center, Hospital No. 52 of the Moscow Healthcare Department, Moscow, Russia; 2) Central Clinical Hospital with Policlinic of the Administrative Directorate of the President of the Russian Federation, Moscow, Russia

Treatment of malignant neoplasms in kidney transplant recipients has distinctive features compared to the non-transplant population. When a tumor is detected in recipients, immunosuppressive therapy is reduced or modified to enhance the natural immune system, followed by treatment. However, some medications that are standard in the non-transplant population are not used or are used only to a limited extent due to the increased risk of kidney graft rejection. The risk of graft rejection, difficulties in therapy, and small patient samples mean that some issues related to cancer treatment in kidney transplant recipients remain controversial and under study.

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About the Authors

Ruslan N. Trushkin, Dr.Sci. (Med.), Head of the Urology Department, Moscow Regional Clinical Research Center, Hospital No. 52 of the Moscow Healthcare Department. Address: 3 Pekhotnaya St., Moscow, 123182; Tel.: +7 (499) 196-18-05; Email: uro52@mail.ru. ORCID: https://orcid.org/0000-0002-3108-0539.
Aleksandr A. Sokolov, Cand.Sci. (Med.), Urologist, Central Clinical Hospital with a Polyclinic of the Administrative Directorate of the President of the Russian Federation. Address: 15 Marshal Timoshenko St., Moscow, 121359; Tel.: +7 (985) 492-35-77; Email: salexdoc@gmail.com. ORCID: https://orcid.org/0009-0007-0302-0428,
SPIN-code: 5887-1880, AuthorID: 889052.
Sergey A. Sokolov – Urologist, Urology Department, Moscow Regional Clinical Research Center, Hospital No. 52 of the Moscow Healthcare Department.
Address: 3 Pekhotnaya St., Moscow, 123182; tel.: +7 (910) 859-47-77; e-mail: sergey.sokolow28@mail.ru. ORCID: https://orcid.org/0009-0004-7016-2360.
Teymur K. Isaev – Dr.Sci. (Med.), Urologist, Urology Department, Moscow Regional Clinical Research Center, Hospital No. 52 of the Moscow Healthcare Department.
Address: 3 Pekhotnaya St., Moscow, 123182; Tel.: +7 (906) 033-26-36; Email: dr.isaev@mail.ru. ORCID: https://orcid.org/0000-0003-3462-8616.
Anastasia M. Isaeva – Gynecologist, Central Clinical Hospital with a Polyclinic of the Administrative Directorate of the President of the Russian Federation.
Address: 15 Marshal Timoshenko St., Moscow, 121359; Tel.: +7 (916) 114-22-83; Email: antropik88@mail.ru.

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